Sukansyöjän kennel Group

While many cases of IgA vasculitis are mild, a subset of patients experience severe disease with organ involvement, requiring intensive monitoring and treatment. The most critical organs affected are the kidneys and gastrointestinal tract, and early detection of complications significantly impacts outcomes.

Kidney involvement is one of the most serious manifestations. Inflammation caused by IgA deposition may lead to hematuria, proteinuria, or even reduced kidney function. Adults are more prone to significant renal complications than children, sometimes necessitating immunosuppressive therapy or close nephrology follow-up. Chronic kidney disease can develop if kidney inflammation is severe or prolonged, emphasizing the importance of early monitoring.

Gastrointestinal complications are another concern. Severe abdominal pain, vomiting, and gastrointestinal bleeding may indicate significant intestinal vasculitis. Rarely, serious events such as bowel perforation, intussusception, or ischemia may occur, requiring emergency surgical intervention. Early recognition of worsening abdominal symptoms allows clinicians to act promptly and prevent life-threatening outcomes.

Systemic inflammation may also affect joints, causing persistent pain, swelling, and limited mobility. Although less dangerous than kidney or gastrointestinal involvement, prolonged joint symptoms can impact quality of life and daily functioning.